On, 26,715 cases of COVID-19 were recorded. On 2 March 2020, Portugal announced the first confirmed case of SARS-CoV-2. The COVID-19 pandemic is a global public health emergency with tremendous consequences for people’s lives and their mental health. This partial mediation suggests that there may be other possible variables (e.g., social connection, self-compassion, gratitude, sense of purpose) that further explain the associations. Psychological resilience played a partial mediating role between depression and all burnout dimensions. The results revealed that depression had not only a directed effect on personal, work- and client-related burnout, but also an indirect small effect on it through resilience. A total of 2008 subjects completed the survey, and a hierarchical regression model was estimated for each burnout dimension. A survey was conducted comprising standardized measures of resilience (Resilience Scale-25 items), depression (subscale of Depression Anxiety Stress Scales-21 items), and burnout (Copenhagen Burnout Inventory Scale-19 items). A cross-sectional study was performed using an online questionnaire distributed via social networks. The aim of this study was to explore the mediating role of resilience in the relationship between depression and burnout (personal, work-related, and client-related). Resilience might protect employees from the negative consequences of chronic stress. During the COVID-19 pandemic, healthcare workers (HCW) have been exposed to multiple psychosocial stressors.
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